Efficacy trial - Nobilis TRT inac. used with Nobilis TRT
Laboratory Trial
Method
- Groups of turkey poults were vaccinated as follows:
- Group 1: vaccinated with Nobilis TRT (7 days) and Nobilis TRT+ND (30 weeks); not challenged
- Group 2: vaccinated with TRT (7 days) and Nobilis TRT+ND (30 weeks) and challenged
- Group 3: vaccinated with Nobilis TRT (7 days) only and challenged
- Group 4: not vaccinated and challenged.
- Egg production was recorded.
- In week 38 the birds were challenged.
- Fully vaccinated but unchallenged birds served as positive controls.
- Non-vaccinated birds were challenged and served as negative controls.
Results
| Group | Nobilis TRT and/or Nobilis TRT+ND | No. in group | Mean TRT antibody titre by ELISA (log2) at weeks of age | |||||
|---|---|---|---|---|---|---|---|---|
| Nobilis TRT | Nobilis TRT+ND | 1 w. | 4 w. | 30 w. | 38 w. | 42 w. | ||
| 1 | + | + | 23 | 10 | 7.6 | <7 | 15.6 (1.3)* | 16.6 (1.2) |
| 2 | + | + | 28 | 10 | 7.6 | <7 | 16.0 (1.7) challenge | 17.9 (0.8) |
| 3 | + | - | 28 | 10 | 8.9 | <7 | <7 challenge | 14.9 (1.7) |
| 4 | - | - | 22 | n.a. | n.a. | <7 | <7 challenge | 15.5 (1.9) |
* Mean titre (standard deviation)
n.a: not available
Inactivated vaccine given at 30 wks challenge at 38 wks
Relative weekly egg production* per group
* Egg production for each group individually set at 100% at 38 weeks of age before challenge, subsequent values for each group/week are related to the percentage at 38 weeks.
Conclusion
Vaccination with Nobilis TRT and Nobilis TRT inac is effective in preventing losses in egg production.
